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Excellent long-term device survival of inflatable penile prosthesis over 27 years

  • Título: Excellent long-term device survival of inflatable penile prosthesis over 27 years
  • Autores: Moncada, I; Krishnappa, P; Martinez-Salamanca, JI; Palma-Hendges, LP; Gonzalez-Garcia, FJ; Hernandez-Fernandez, C; Lledo-Garcia, E
  • Revista: ASIAN JOURNAL OF ANDROLOGY
  • IF: 2,7
  • Quartil: Q2
  • DOI: 10.4103/aja2024112
  • Centro: Hospital Universitario La Zarzuela
  • Departamento/servicio: Urología

Abstract:

The study aimed to assess the long-term device survival of a 3-piece inflatable penile prosthesis (PP) in patients with erectile dysfunction (ED). This retrospective observational longitudinal study involved patients with drug-refractory ED who underwent primary 3-piece inflatable PP implantation at a single center from 1992 to 2019. The outcomes included complications of various inflatable PP models, and Kaplan-Meier analysis was used to estimate the probability of PP survival. Of the total 426 patients, 140 (32.9%) were implanted in the period of 1992-2000, 128 (30.0%) in the period of 2001-2008, and 158 (37.1%) in the period of 2009-2019. The PP used in the study included AMS 700 CX (62.0%, n = 264), AMS 700 CXR (7.7%, n = 33), AMS Ultrex Plus (10.3%, n = 44), and Alpha I (20.0%, n = 85). The overall complication rate was 28.2% (120/426), and the majority happened after 6 months. The causes of device removal included mechanical failure (11.0%, n = 47), infection (3.9%, n = 17), cylinder extrusion (6.3%, n = 27), and unspecified (0.2%, n = 1). Of the total mechanical failures (n = 47), 18 (38.3%) occurred in the cylinders, 10 (21.3%) occurred in the pump, 7 (14.9%) occurred in the reservoir, 6 (12.8%) occurred in the connections, and 6 (12.8%) were nonspecific. Global average survival rates of the PP at 1 year, 5 years, 10 years, and 15 years were 96.2%, 86.7%, 77.5%, and 58.7%, respectively. The 3-piece inflatable PP has an excellent device survival rate at 5 years and 10 years. (Summary); Krishnappa, P (corresponding author), La Zarzuela Univ Hosp, Dept Urol & Robot Surg, Madrid 28023, Spain.;Krishnappa, P (corresponding author), NU Hosp, Dept Urol & Robot Surg, Androl Div, AndroNeo,Orchidz Hlth, Bengaluru 560010, Karnataka, India. (Author of contact)

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